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Endoscopic Tactile Capsule for Non-Polypoid Colorectal Tumour Detection

Camboni, D; Massari, L; Chiurazzi, M; Calio, R; Alcaide, JO; D'Abbraccio, J; Mazomenos, E; ... Ciuti, G; + view all (2021) Endoscopic Tactile Capsule for Non-Polypoid Colorectal Tumour Detection. IEEE Transactions on Medical Robotics and Bionics , 3 (1) pp. 64-73. 10.1109/tmrb.2020.3037255. Green open access

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Abstract

An endoscopic tactile robotic capsule, embedding miniaturized MEMS force sensors, is presented. The capsule is conceived to provide automatic palpation of non-polypoid colorectal tumours during colonoscopy, since it is characterized by high degree of dysplasia, higher invasiveness and lower detection rates with respect to polyps. A first test was performed employing a silicone phantom that embedded inclusions with variable hardness and curvature. A hardness-based classification was implemented, demonstrating detection robustness to curvature variation. By comparing a set of supervised classification algorithms, a weighted 3-nearest neighbor classifier was selected. A bias force normalization model was introduced in order to make different acquisition sets consistent. Parameters of this model were chosen through a particle swarm optimization method. Additionally, an ex-vivo test was performed to assess the capsule detection performance when magnetically-driven along a colonic tissue. Lumps were identified as voltage peaks with a prominence depending on the total magnetic force applied to the capsule. Accuracy of 94 % in hardness classification was achieved, while a 100 % accuracy is obtained for the lump detection within a tolerance of 5 mm from the central path described by the capsule. In real application scenario, we foresee our device aiding physicians to detect tumorous tissues.

Type: Article
Title: Endoscopic Tactile Capsule for Non-Polypoid Colorectal Tumour Detection
Open access status: An open access version is available from UCL Discovery
DOI: 10.1109/tmrb.2020.3037255
Publisher version: https://doi.org/10.1109/tmrb.2020.3037255
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Computer Science
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng
URI: https://discovery.ucl.ac.uk/id/eprint/10123626
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