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Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device

Gil, B; Li, B; Gao, A; Yang, G-Z; (2020) Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device. ACS Applied Electronic Materials , 2 (8) pp. 2669-2677. 10.1021/acsaelm.0c00538. Green open access

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Abstract

Real-time monitoring of intrabody pressures can benefit from the use of miniaturized force sensors during surgical interventions or for the recovery period thereafter. Herein, we present a force sensor made of poly(vinylidene fluoride)-co-trifluoroethylene (P(VDF-TrFE)) with a simple fabrication process that has been integrated into the tip of a medical catheter for intraluminal pressure monitoring, as well as into an implantable device with a power consumption of 180 μW obtained by the near-field communication (NFC) interface to monitor the arterial pulse at the subcutaneous level (≤1 cm). The pressure range supported by the sensor is below 40 kPa, with a signal responsivity of 0.63 μV/Pa and a mean lifetime expectancy of 400 000 loading cycles inside physiological conditions (12 kPa). The proposed sensor has been tested experimentally with synthetic anatomical models for the lungs (bronchoscopy) and subcutaneous tissue, as well as directly above the human carotid and radial arteries. Information about these pressure levels can provide insights about tissue homeostasis inside the body as fluid dynamics are altered in some health conditions affecting the hemodynamic and endocrine body systems, whereas for surgical interventions, precise control and estimation of the pressure exerted by a catheter over the internal walls are necessary to avoid endothelium injuries that lead to bleeding, liquid extravasation, or flow alteration associated with atheroma formation.

Type: Article
Title: Miniaturized Piezo Force Sensor for a Medical Catheter and Implantable Device
Open access status: An open access version is available from UCL Discovery
DOI: 10.1021/acsaelm.0c00538
Publisher version: https://doi.org/10.1021/acsaelm.0c00538
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Piezo sensor medical catheter implantable device energy harvesting intrabody pressure monitoring
UCL classification: UCL
UCL > Provost and Vice Provost Offices > UCL BEAMS
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office
UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Maths and Physical Sciences > MAPS Faculty Office > Institute for Materials Discovery
URI: https://discovery.ucl.ac.uk/id/eprint/10134878
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