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Arterial pulse wave modelling and analysis for vascular age studies: a review from VascAgeNet

Alastruey, Jordi; Charlton, Peter H; Bikia, Vasiliki; Paliakaitė, Birute; Hametner, Bernhard; Bruno, Rosa Maria; Mulder, Marijn P; ... Westerhof, Berend E; + view all (2023) Arterial pulse wave modelling and analysis for vascular age studies: a review from VascAgeNet. American Journal of Physiology - Heart and Circulatory Physiology , 325 (1) H1-H29. 10.1152/ajpheart.00705.2022. Green open access

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Abstract

Arterial pulse waves (PWs) such as blood pressure and photoplethysmogram (PPG) signals contain a wealth of information on the cardiovascular (CV) system that can be exploited to assess vascular age and identify individuals at elevated CV risk. We review the possibilities, limitations, complementarity, and differences of reduced-order, biophysical models of arterial PW propagation, as well as theoretical and empirical methods for analyzing PW signals and extracting clinically relevant information for vascular age assessment. We provide detailed mathematical derivations of these models and theoretical methods, showing how they are related to each other. Finally, we outline directions for future research to realize the potential of modeling and analysis of PW signals for accurate assessment of vascular age in both the clinic and in daily life.

Type: Article
Title: Arterial pulse wave modelling and analysis for vascular age studies: a review from VascAgeNet
Location: United States
Open access status: An open access version is available from UCL Discovery
DOI: 10.1152/ajpheart.00705.2022
Publisher version: https://doi.org/10.1152/ajpheart.00705.2022
Language: English
Additional information: Copyright © 2023 The Authors. Licensed under Creative Commons Attribution CC-BY 4.0. Published by the American Physiological Society.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Population Science and Experimental Medicine
URI: https://discovery.ucl.ac.uk/id/eprint/10168643
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