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Accelerating precision ophthalmology: recent advances

Rahman, L; Hafejee, A; Anantharanjit, R; Wei, W; Cordeiro, MF; (2022) Accelerating precision ophthalmology: recent advances. Expert Review of Precision Medicine and Drug Development , 7 (1) pp. 150-161. 10.1080/23808993.2022.2154146. Green open access

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Abstract

Introduction: The future of ophthalmology is precision medicine. With a growing incidence of lifestyle-associated ophthalmic disease such as diabetic retinopathy, the use of technology has the potential to overcome the burden on clinical specialists. Advances in precision medicine will help improve diagnosis and better triage those with higher clinical need to the appropriate experts, as well as providing a more tailored approach to treatment that could help transform patient management. Areas covered: A detailed literature review was conducted using OVID Medline and PubMed databases to explore advances in precision medicine within the areas of retinal disease, glaucoma, cornea, cataracts and uveitis. Over the last three years [2019–2022] are explored, particularly discussing technological and genomic advances in screening, diagnosis, and management within these fields. Expert opinion: Artificial intelligence and its subspecialty deep learning provide the most substantial ways in which diagnosis and management of ocular diseases can be further developed within the advancing field of precision medicine. Future challenges include optimal training sets for algorithms and further developing pharmacogenetics in more specialized areas.

Type: Article
Title: Accelerating precision ophthalmology: recent advances
Open access status: An open access version is available from UCL Discovery
DOI: 10.1080/23808993.2022.2154146
Publisher version: https://doi.org/10.1080/23808993.2022.2154146
Language: English
Additional information: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Ophthalmology
URI: https://discovery.ucl.ac.uk/id/eprint/10178902
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