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Beyond Tissue replacement: The Emerging role of smart implants in healthcare

Abyzova, Elena; Dogadina, Elizaveta; Rodriguez, Raul D; Petrov, Ilia; Kolesnikova, Yuliana; Zhou, Mo; Liu, Chaozong; (2023) Beyond Tissue replacement: The Emerging role of smart implants in healthcare. Materials Today Bio , 22 , Article 100784. 10.1016/j.mtbio.2023.100784. Green open access

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Abstract

Smart implants are increasingly used to treat various diseases, track patient status, and restore tissue and organ function. These devices support internal organs, actively stimulate nerves, and monitor essential functions. With continuous monitoring or stimulation, patient observation quality and subsequent treatment can be improved. Additionally, using biodegradable and entirely excreted implant materials eliminates the need for surgical removal, providing a patient-friendly solution. In this review, we classify smart implants and discuss the latest prototypes, materials, and technologies employed in their creation. Our focus lies in exploring medical devices beyond replacing an organ or tissue and incorporating new functionality through sensors and electronic circuits. We also examine the advantages, opportunities, and challenges of creating implantable devices that preserve all critical functions. By presenting an in-depth overview of the current state-of-the-art smart implants, we shed light on persistent issues and limitations while discussing potential avenues for future advancements in materials used for these devices.

Type: Article
Title: Beyond Tissue replacement: The Emerging role of smart implants in healthcare
Location: England
Open access status: An open access version is available from UCL Discovery
DOI: 10.1016/j.mtbio.2023.100784
Publisher version: https://doi.org/10.1016/j.mtbio.2023.100784
Language: English
Additional information: Copyright © 2023 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
Keywords: Smart implants; Implantable electronics; Sensors and stimulation devices; Implant materials; Remote health monitoring; Continuous monitoring
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Ortho and MSK Science
URI: https://discovery.ucl.ac.uk/id/eprint/10179097
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