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Chaos begets order: asynchronous cell contractions drive epithelial morphogenesis

Abstract

Apical cell contraction triggers tissue folding and invagination in epithelia. During Drosophila gastrulation, ventral furrow formation was thought to be driven by smooth, purse-string-like constriction of an acto-myosin belt underlying adherens junctions. Now Martin et al. report in Nature that ventral furrow formation is triggered by asynchronous pulsed contractions of the apical acto-myosin cortex in individual cells

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MPG.PuRe

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Last time updated on 15/06/2019

This paper was published in MPG.PuRe.

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