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Copyright @ 2007 INFORMSThe variable neighborhood search metaheuristic is applied to the primal simple plant-location problem and to a reduced dual obtained by exploiting the complementary slackness conditions. This leads to (i) heuristic resolution of (metric) instances with uniform fixed costs, up to n = 15,000 users, and m = n potential locations for facilities with an error not exceeding 0.04%; (ii) exact solution of such instances with up to m = n = 7,000; and (iii) exact solutions of instances with variable fixed costs and up to m = n = 15, 000.This work is supported by NSERC Grant 105574-02; NSERC Grant OGP205041; and partly by the Serbian Ministry of Science, Project 1583
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