We are not able to resolve this OAI Identifier to the repository landing page. If you are the repository manager for this record, please head to the Dashboard and adjust the settings.
Due to the presence of the indole ring in a number of bioactive compounds, novel methods for the preparation of polyfunctionalized indole derivatives are of great interest. The combined use of Lewis acid catalysis and microwave irradiation furnished satisfactory results in the Yonemitsu-type trimolecular condensation of indoles with aldehydes and 1,3-dicarbonyl compounds, such as malonates and acetoacetates.
The main advantage of this procedure is the use of a catalytic amount of the Lewis acid and reduction in reaction time. The one pot procedure avoids the isolation and purification of intermediates, thus making the process more environmentally sustainable. The protocol has also been successfully applied to the preparation of novel indole-coumarin derivatives of potential biological interes
Is data on this page outdated, violates copyrights or anything else? Report the problem now and we will take corresponding actions after reviewing your request.