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oaioai:doaj.org/article:6175926f5756410892d93fc04ae54b65

Ion-Sensitive Field-Effect Transistor for Biological Sensing

Authors
Publication date
1 September 2009
Publisher
'MDPI AG'
Doi

    Abstract

    In recent years there has been great progress in applying FET-type biosensors for highly sensitive biological detection. Among them, the ISFET (ion-sensitive field-effect transistor) is one of the most intriguing approaches in electrical biosensing technology. Here, we review some of the main advances in this field over the past few years, explore its application prospects, and discuss the main issues, approaches, and challenges, with the aim of stimulating a broader interest in developing ISFET-based biosensors and extending their applications for reliable and sensitive analysis of various biomolecules such as DNA, proteins, enzymes, and cells

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