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Immunofluorescence analysis of muscle basement membrane and plasma membrane.
Abstract
<p>The expression of DAPI, laminin, and dystrophin was examined in wild-type (WT; upper panel) and p21 knockout (KO; lower panel) mice. (A) Expression in control, (B) Expression in 3 days, (C) Expression in 14 days, and (D) Expression in 28 days post-operation. (Scale bar = 50μm). (E) Quantification of laminin expression, (F) Quantification of dystrophin expression. (A-F) The injured membrane structure was almost repaired 14 days after injury in WT group, but not in the p21 KO group (p < 0.05).</p- Image
- Figure
- Biological Sciences
- wt
- muscle cell proliferation
- p 21 deficiency
- p 21 KO mice
- p 21 knockout
- P 21 Deficiency Delays Regeneration
- Skeletal Muscular Tissue
- muscle regeneration
- vivo healing process
- muscle injury model
- p 21 function
- muscle injury causes
- cell cycle checkpoint control
- p 21
- p 21KO mice
- Cyclin D 1 mRNA expression
- pcna