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CADM1 expression is upregulated in KSHV-infected cells.
Abstract
<p>(A-B) Quantitative real-time PCR (qRT-PCR) analysis of CADM1 from HeLa and primary human B cells with and without KSHV infection. (C-D) qRT-PCR analysis of CADM1 from KSHV-associated PEL cell lines (BC-1, BC-3, BCBL-1, and UM-PEL-3) (error bars, s.e.m. of triplicate samples). (E-G) Western blot analysis of CADM1 and LANA in KSHV-infected HeLa, human primary B cells, and PEL cell lines (BC-1, BC-3, BCBL-1, and UM-PEL-3).</p- Image
- Figure
- Biochemistry
- Microbiology
- Cell Biology
- Immunology
- Cancer
- Mental Health
- Hematology
- Infectious Diseases
- Virology
- KSHV life cycle
- survival
- KSHV-infected cells
- Cell Adhesion Molecule 1
- PDZ binding motif
- CADM 1
- KSHV-encoded vGPCR-and vFLIP-mediated
- CADM 1 interaction
- oncogenic viruses
- PBMC
- NF
- IKK
- Membrane lipid raft
- KSHV-associated PEL cells
- MCD
- role
- activation