Rapidly exploring structural and dynamic properties of signaling networks using PathwayOracle-0

Abstract

Wo High nodes, EGF and LKB-auto. EGF will be initialized with a token-count of 10, LKB-auto with a token-count of 3. The token-count of AMPK will be zero for the duration of the simulation. (b) The setup window for the differential simulator. Two different scenarios are being compared through simulation: different token assignments are being tried with EGF and LKB-auto, with and without AMPK being fixed low. (c) The plot window for the marking series generated by a simulation. Observe that the signaling nodes whose activity-levels are plotted correspond to those selected in the checklist directly to the left of the plot.<p><b>Copyright information:</b></p><p>Taken from "Rapidly exploring structural and dynamic properties of signaling networks using PathwayOracle"</p><p>http://www.biomedcentral.com/1752-0509/2/76</p><p>BMC Systems Biology 2008;2():76-76.</p><p>Published online 19 Aug 2008</p><p>PMCID:PMC2527501.</p><p></p