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An asymmetric synthesis of beta-lactams: on the use of chiral oxazolidones in the Kinugasa reaction

Abstract

Enantiopure cis and trans -lactams 3a–e and 4a–e, respectively, have been synthesized via cycloaddition between chiral oxazolidinyl propynes 1a–b and nitrones 2a–d, in the presence of cuprous iodide (the Kinugasa reaction)

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Archivio istituzionale della ricerca - Università di Ferrara

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Last time updated on 12/11/2016

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