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Enantioselective synthesis of (-)-meroquinene through tandem Michael reaction methodology

Abstract

An enantioselective approach to the synthesis of non natural (-)-meroquinene based on sequential inter- and intramolecular Michael reaction between (L)-menthyl N-benzyl-5-amino-2E-pentenoate and 1-acetyloxy-4-methoxymethyloxy-2-nitrobutane, acting as surrogate of 2-nitro-1,3-butadiene, is described

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Archivio istituzionale della ricerca - Università di Ferrara

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Last time updated on 12/11/2016

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