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We identify recurrent ingredients in the antithetic sampling literature leading to a unified sampling framework. We introduce a new class of antithetic schemes that includes the most used antithetic proposals. This perspective enables the derivation of new properties of the sampling schemes: i) optimality in the Kullback--Leibler sense; ii) closed-form multivariate Kendall's τ and Spearman's ρ; iii) ranking in concordance order and iv) a central limit theorem that characterizes stochastic behaviour of Monte Carlo estimators when the sample size tends to infinity. The proposed simulation framework inherits the simplicity of the standard antithetic sampling method, requiring the definition of a set of reference points in the sampling space and the generation of uniform numbers on the segments joining the points. We provide applications to Monte Carlo integration and Markov Chain Monte Carlo Bayesian estimation
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