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This is a post print of a paper from UK e-Science All Hands Meeting 10th-13th September 2007 published by National e-Science Centre. http://www.allhands.org.uk/2007/.Paediatric endocrinology is a highly specialised area of clinical medicine with many experts with specific knowledge distributed over a wide geographical area. The European Society for Paediatric Endocrinology (ESPE) is an example of such a body of experts that require regular collaboration and sharing of data and knowledge. This paper describes work, developed as a corollary to the VOTES project [1] and implementing similar architectures, to provide a data grid that allows information to be efficiently distributed between collaborating partners, and also allows wide-scale analyses to be run over the entire data-set, which necessarily involves crossing domain boundaries and negotiating data access between administrations that only trust each other to a limited degree.10th-13th Septembe
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