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oaioai:ojs.pkp.sfu.ca:article/2228

Synthesis, characterization and antimitotic activity of N-benzyl piperidin 4-one oxime

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Publication date
15 January 2019
Publisher
Vinita Nagar, Society of Pharmaceutical Technocrats, 1/7756, Street no. 1, East Gorakh Park, Shahdara, Delhi, India 110032
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    Abstract

    The aim of this study was to synthesize, characterization and antimitotic activity of N-Benzyl piperidin 4-one oxime derivative. The synthesized compound was characterized by IR, 13C and 1H NMR spectral studies. The synthesized compound was subjected to antimitotic studies of alliumcepa root meristamatic cells. The mitotic activity was observed in 3 different concentrations of N-Benzyl piperidin 4-one oxime. Our findings support the reported therapeutic use of this compound as a antimitotic or anticancer agent in the Indian system of medicine. Keywords: N-Benzyl piperidin 4-one oxime, meristamatic cells, mitotic index

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    Journal of Drug Delivery and Therapeutics (JDDT)

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    Last time updated on 17/10/2019

    This paper was published in Journal of Drug Delivery and Therapeutics (JDDT).

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