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An emerging technology Digital Microfluidics Biochips, an integrating concept of electronics and biology is anticipated to play an important role in the area of medical diagnostics, drug discovery, DNA sequencing, toxicity supervising and other bio-chemical applications. This bio-microelectromechanical system is supposed to have defects if it fails to accomplish the specified assignment dedicated to it. This paper focuses on different possible cases responsible for the misbehavior of the bio-MEMS
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