Metabolic and hormonal responses to altered carbohydrate availability and its effect on fatigue development

Abstract

Includes bibliographical references (leaves 200-220).The main aims of the series of studies comprising this thesis were to investigate the effect of altered endogenous carbohydrate (CHO) availability, achieved primarily by pre-exercise dietary manipulation and antecedent exercise exposure, on interindividual variability in metabolic and hormonal responses to dynamic, steady-state exercise. Further, this thesis examined the impact of altered blood glucose availability on fatigue development during prolonged exercise. In this regard, it was hypothesized that endogenous CHO availability and the associated metabolic sequelae would impact on effort perception during exercise and fatigue development