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Control engineering (in the broad sense of the term) has become an important enabling technology in many areas of medicine. Prominent examples include the artificial pancreas, closed-loop anesthesia, and personalized drug dosing strategies in neurology, oncology, endocrinology, and psychiatry. It is a testament to the power of control systems that allow individualizing treatment by providing mechanisms for linking treatment goals to treatment regimens, thus achieving a desired therapeutic effect. Consequently, the arrival of control systems engineering to the clinic enables the visionary concept of "treat the patient, not the disease" technologically and economically feasible.</p
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