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A biophysical model for analysis of transcription factor interaction and binding site arrangement from genome-wide binding data
Abstract
10.1371/journal.pone.0008155PLoS ONE412e815- Article
- transcription factor NANOG
- Drosophila protein
- homeodomain protein
- transcription factor
- article
- binding affinity
- binding site
- cis isomer
- computer prediction
- controlled study
- DNA binding
- DNA microarray
- Drosophila
- Drosophila melanogaster
- drosophila pseudoobscura
- embryonic stem cell
- gene control
- gene interaction
- gene location
- gene targeting
- genetic analysis
- genetic association
- genetic conservation
- genetic transcription
- genome
- protein motif
- quantitative study
- regulatory sequence
- sequence homology
- theoretical model
- animal
- biological model
- biology
- biophysics
- chromatin immunoprecipitation
- genetic database
- genetics
- genome
- metabolism
- mouse
- nucleotide sequence
- protein binding
- receiver operating characteristic
- reproducibility
- Drosophila melanogaster
- Drosophila pseudoobscura
- Animals
- Base Sequence
- Binding Sites
- Biophysical Phenomena
- Chromatin Immunoprecipitation
- Computational Biology
- Databases, Genetic
- Drosophila melanogaster
- Drosophila Proteins
- Genome
- Homeodomain Proteins
- Mice
- Models, Genetic
- Protein Binding
- Reproducibility of Results
- ROC Curve
- Transcription Factors