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A fuzzy logic-based color histogram analysis technique is presented for discriminating benign skin lesions from malignant melanomas in dermoscopy images. The approach extends previous research for utilizing a fuzzy set for skin lesion color for a specified class of skin lesions, using alpha-cut and support set cardinality for quantifying a fuzzy ratio skin lesion color feature. Skin lesion discrimination results are reported for the fuzzy clustering ratio over different regions of the lesion over a data set of 517 dermoscopy images consisting of 175 invasive melanomas and 342 benign lesions. Experimental results show that the fuzzy clustering ratio applied over an eight-connected neighborhood on the outer 25% of the skin lesion with an alpha-cut of 0.08 can recognize 92.6% of melanomas with approximately 13.5% false positive lesions. These results show the critical importance of colors in the lesion periphery. Our fuzzy logic-based description of lesion colors offers relevance to clinical descriptions of malignant melanoma
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