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oaioai:spiral.imperial.ac.uk:10044/1/39321

An Integrated Platform for Differential Electrochemical and ISFET Sensing

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Publication date
1 May 2016
Publisher
IEEE
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    Abstract

    A fully-integrated differential biosensing platform on CMOS is presented for miniaturized enzyme-based electrochemical sensing. It enables sensor background current elimination and consists of a differential sensor array and a differential readout IC (DiRIC). The sensor array includes a four-electrode sensor for amperometric electrochemical sensing, as well as a differential ISFET-based pH sensor to calibrate the biosensors. The ISFET is biased in weak inversion and co-designed with DiRIC to enable pH measurements from 1 to 14 with resolution of 0.1 pH. DiRIC enables differential current measurement in the range of ¿¿100 ¿¿A with more than 120dB dynamic range

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    Spiral - Imperial College Digital Repository

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    This paper was published in Spiral - Imperial College Digital Repository.

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